Moving a TAD closer to unravelling chromosome architecture
نویسندگان
چکیده
منابع مشابه
A TAD closer to ATM
Ataxia telangiectasia mutated (ATM) has been known for decades as the main kinase mediating the DNA double-strand break response. Our recent findings suggest that its major role at the sites of breaks likely resides in its ability to modify both the local chromatin landscape and the global chromosome organization in order to promote repair accuracy.
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ژورنال
عنوان ژورنال: Nature Reviews Molecular Cell Biology
سال: 2015
ISSN: 1471-0072,1471-0080
DOI: 10.1038/nrm4092